每周二、四为您推送近期幽门螺杆菌相关文献摘要，追踪学术进展。
DelayinretreatmentofHelicobacterpyloriinfectionincreasesriskofUpperGastrointestinalBleeding
延迟对幽门螺杆菌感染的再治疗会增加上消化道出血的风险
Abstract摘要
BackgroundandAims:
Littleisknownaboutriskofuppergastrointestinalbleeding(UGIB)inpatientsfailedbyHelicobacterpylorieradicationtherapy.Weinvestigatedtheeffectsofdifferenttimeuntilretreatment,afterfailureofinitialH.pylorieradicationtherapy,onsubsequentriskofUGIB.
背景和目的：
人们对幽门螺杆菌根除疗法失败的患者发生上消化道出血（UGIB）的风险知之甚少。我们研究了初次幽门螺杆菌根除治疗失败后，直至再治疗的不同时间对后续UGIB风险的影响。
Methods:
Weperformedaterritory-wideretrospectivecohortstudyof70,patientswithHpyloriinfectionwhohadreceivedtheirfirstcourseofclarithromycin-basedtripletherapyfromJanuarythroughDecemberinHongKong.Patientswhorequiredretreatmentafterfailedinitialtherapy(n=,11.8%)werecategorizedbasedontimebetweeninitialandfinalHpylorieradication(3monthsorless,3–12months,andmorethan12months).Wecollectedclinicaldatafrom30daysafterprescriptionofthelastcourseofHpyloritherapyuntilhospitalizationfornon-varicealUGIB,death,ortheendofthestudy(30Jun;medianfollow-uptime,7.65years).Theprimaryout